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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2050142Generated: October 30, 2026

2-(Chloromethyl)-1,3-thiazole → 1-Nitro-2-(propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethylene

https://huagongshe.com/reaction/2050142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-1,3-thiazoleHCID 14090864—
Reactant1-Nitro-2-(2-propynylamino)-2-(2-mercaptoethyl)ethyleneHCID 73683998—
Product1-Nitro-2-(propynylamino)-2-{2-[(thiazol-2-yl)methylthio]ethylamino}ethyleneHCID 70597158—

Reaction Steps

The product of Step A is reacted in a non-reactive solvent with about an equimolar amount of 2-chloromethylthiazole and about one equivalent of base, and the title product is thereby produced.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04200578
Source datasetuspto-grants-1980_04
ORD IDord-fd423d1c94a945868f2609729b2912de
Source noteuspto-grants-1980_04