N-[1-(Methylsulfanyl)-2-nitroethenyl]prop-2-yn-1-amine → HCID 178457408, compound

HRID 2050156Notes

Reaction equation

HRID 2050156 reaction equation
CS[C:3]([NH:8][CH2:9][C:10]#[CH:11])=[CH:4][N+:5]([O-:7])=[O:6].[NH:12]([C:16]1[S:17][CH:18]=[C:19]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])[N:20]=1)[C:13]([NH2:15])=[NH:14]>>[N+:5]([CH:4]=[C:3]([NH:8][CH2:9][C:10]#[CH:11])[NH:25][CH2:24][CH2:23][S:22][CH2:21][C:19]1[N:20]=[C:16]([NH:12][C:13]([NH2:15])=[NH:14])[S:17][CH:18]=1)([O-:7])=[O:6]

Participants

3

Reactant 2

HCID 71401969N-[1-(Methylsulfanyl)-2-nitroethenyl]prop-2-yn-1-amineHCID 1785127232-[4-(2-Aminoethylsulfanylmethyl)-1,3-thiazol-2-yl]guanidine

Product 1

HCID 178457408HCID 178457408, compound

Procedure

1-Methylthio-1-(2-propynylamino)-2-nitroethylene (prepared in Example 2, Step A, above) is reacted in an inert solvent with about an equimolar amount of 2-[(2-guanidinothiazol-4-yl)methylthio]ethylamine to produce, after workup, the title product.

Workup

  1. customto produce

Sources & evidence

ORD record
ord-7447d5ade7b2472da5d80e1b83e26162
Source dataset
uspto-grants-1980_04
Patent number
US04200578

Reaction notes

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