HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethyl phosphite → Diethyl 4-fluorophenylthiomethylphosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | 1-[(Chloromethyl)thio]-4-fluorobenzene | HCID 20161342 | — |
| Product | Diethyl 4-fluorophenylthiomethylphosphonate | HCID 23349659 | 95.7% |
Reaction Steps
This compound was prepared in the manner of Example 3.B., using 59.3 grams (0.34 mole) of 4-fluorophenylthiomethyl chloride and 71.3 grams (0.43 mole) of triethylphosphite. The residue was distilled under reduced pressure to give 89.4 grams (95.7%) of diethyl 4-fluorophenylthiomethylphosphonate; b.p. 147° C./0.6 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04200644 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-15ecc395413f4f4db5fc1cff77f3e195 |
| Source note | uspto-grants-1980_04 |