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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 205019Generated: October 29, 2026

6-(6-acetamidopyrimidin-4-yl)oxy-N-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide → 6-(6-aminopyrimidin-4-yl)oxy-N-[4-[(4-propan-2-ylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide

https://huagongshe.com/reaction/205019

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-(6-acetamidopyrimidin-4-yl)oxy-N-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamideHCID 67405669—
Reactant6-((6-Acetamidopyrimidin-4-yl)oxy)-N-(4-((4-isopropylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-1-naphthamideHCID 67405731—
Product6-(6-aminopyrimidin-4-yl)oxy-N-[4-[(4-propan-2-ylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]naphthalene-1-carboxamideHCID 67407319—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-51bf2e9f6986404f85c898e586b13539
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)