HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4,5-dichloro-2-nitrophenyl)-4-(diphenylmethyl)-1-piperazinepropanamine → 4,5-dichloro-N1-{3-[4-(diphenylmethyl)-1-piperazinyl]propyl}-1,2-benzenediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4,5-dichloro-2-nitrophenyl)-4-(diphenylmethyl)-1-piperazinepropanamine | HCID 20506343 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4,5-dichloro-N1-{3-[4-(diphenylmethyl)-1-piperazinyl]propyl}-1,2-benzenediamine | HCID 53753576 | — |
Reaction Steps
A mixture of 8 parts of N-(4,5-dichloro-2-nitrophenyl)-4-(diphenylmethyl)-1-piperazinepropanamine and 200 parts of methanol is hydrogenated at normal pressure and at room temperature with 2 parts of Raney-nickel catalyst. After the calculated amount of hydrogen is taken up, the catalyst is filtered off and the filtrate is evaporated, yielding 4,5-dichloro-N1 -{3-[4-(diphenylmethyl)-1-piperazinyl]propyl}-1,2-benzenediamine as an oily residue.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04200641 |
| Source dataset | uspto-grants-1980_04 |
| ORD ID | ord-651831c976464b66a75b1872c2120e3b |
| Source note | uspto-grants-1980_04 |