HCID 20342607, compound → HCID 20342617, compound

HRID 2050372Notes

Reaction equation

[ClH:1].[OH:2][C:3]1[CH:12]=[CH:11][C:10]([CH:13]([OH:31])[CH2:14][N:15]2[CH2:20][CH:19]=[C:18]([N:21]3[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[NH:23][C:22]3=[O:30])[CH2:17][CH2:16]2)=[CH:9][C:4]=1[C:5]([O:7]C)=O.Cl.OC1C=CC(C(O)C[N:46]2CCC(N3C4C=CC=CC=4NC3=O)CC2)=CC=1C(OC)=O>>[ClH:1].[OH:2][C:3]1[CH:12]=[CH:11][C:10]([CH:13]([OH:31])[CH2:14][N:15]2[CH2:20][CH:19]=[C:18]([N:21]3[C:25]4[CH:26]=[CH:27][CH:28]=[CH:29][C:24]=4[NH:23][C:22]3=[O:30])[CH2:17][CH2:16]2)=[CH:9][C:4]=1[C:5]([NH2:46])=[O:7]

Participants

Reactant 2

HCID 20342607HCID 20342607, compound

HCID 20342610HCID 20342610, compound

Product 1

HCID 20342617HCID 20342617, compound

Procedure

Following essentially the same procedure but substituting methyl 2-hydroxy-5-[1-hydroxy-2-[4-(2-oxo-1-benzimidazolinyl)-1,2,3,6-tetrahydro-1-pyridyl]ethyl]benzoate hydrochloride for the methyl 2-hydroxy-5-[1-hydroxy-2-[4-(2-oxo-1-benzimidazolinyl)piperidino]ethyl]benzoate hydrochloride above results in the formation of 2-hydroxy-5-[1-hydroxy-2-[4-(2-oxo-1-benzimidazolinyl)-1,2,3,6-tetrahydro-1-pyridyl]ethyl]benzamide hydrochloride.

Sources & evidence

ORD record: ord-93c1233b6deb424c878b70af8e253a10
Source dataset: uspto-grants-1980_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04200755

Reaction notes

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