4-Octyloxybenzoyl chloride → HCID 14513181, compound

HRID 2050415Notes

Reaction equation

HRID 2050415 reaction equation
[CH3:1][C@@H:2]([CH2:18][CH3:19])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH:9]([C:11]1[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=1)[CH3:10].[CH2:20]([O:28][C:29]1[CH:37]=[CH:36][C:32]([C:33](Cl)=[O:34])=[CH:31][CH:30]=1)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]>>[CH2:20]([O:28][C:29]1[CH:30]=[CH:31][C:32]([C:33]([O:17][C:14]2[CH:13]=[CH:12][C:11]([CH:9]([O:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C@@H:2]([CH3:1])[CH2:18][CH3:19])[CH3:10])=[CH:16][CH:15]=2)=[O:34])=[CH:36][CH:37]=1)[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27]

Participants

3

Reactant 2

HCID 27602504-Octyloxybenzoyl chlorideHCID 15044497HCID 15044497, compound

Product 1

HCID 14513181HCID 14513181, compound

Procedure

The procedure of Example 26 was followed except for use of (+)-4-(1-(6-(S)-methyloctyloxy)ethyl)phenol in place of (+)-4-(1-methoxyethyl)phenol and 4-octyloxybenzoic acid chloride in place of 4'-octyloxy-4-biphenylcarboxylic acid chloride to obtain (+)-4-(1-(6(S)-methyloctyloxy)ethyl)phenyl 4-octyloxy-benzoate. [α]D20 =+44.0° (c=1, CHCl3)

Sources & evidence

ORD record
ord-ebae261141114b56a830741464d34551
Source dataset
uspto-grants-1991_05
Patent number
US05013479

Reaction notes

Loading…