[3-cyclopropyl-4-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]pyrrolidin-1-yl]-(1H-indol-7-yl)methanone → [3-Cyclopropyl-4-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]pyrrolidin-1-yl]-(1-prop-2-enylindol-7-yl)methanone

HRID 205044Notes

Reaction equation

HRID 205044 reaction equation
[C:1](=[O:2])([OH:3])[c:4]1[cH:5][cH:6][cH:7][c:8]2[cH:9][cH:10][n:11]([CH2:13][CH:14]=[CH2:15])[c:12]12.[nH:16]1[c:17]2[c:18]([cH:19][cH:20][cH:21][c:22]2[C:23](=[O:24])[N:27]2[CH2:28][CH:29]([CH2:35][N:36]3[CH2:37][CH2:38][CH:39]([c:42]4[cH:43][cH:44][c:45]([F:48])[cH:46][cH:47]4)[CH2:40][CH2:41]3)[CH:30]([CH:32]3[CH2:33][CH2:34]3)[CH2:31]2)[cH:25][cH:26]1>>[C:1](=[O:3])([c:4]1[cH:5][cH:6][cH:7][c:8]2[cH:9][cH:10][n:11]([CH2:13][CH:14]=[CH2:15])[c:12]12)[N:27]1[CH2:28][CH:29]([CH2:35][N:36]2[CH2:37][CH2:38][CH:39]([c:42]3[cH:43][cH:44][c:45]([F:48])[cH:46][cH:47]3)[CH2:40][CH2:41]2)[CH:30]([CH:32]2[CH2:33][CH2:34]2)[CH2:31]1

Participants

3

Reactant 2

HCID 9846369[3-cyclopropyl-4-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]pyrrolidin-1-yl]-(1H-indol-7-yl)methanoneHCID 226244697-carboxy-N-allylindole

Product 1

HCID 9913260[3-Cyclopropyl-4-[[4-(4-fluorophenyl)piperidin-1-yl]methyl]pyrrolidin-1-yl]-(1-prop-2-enylindol-7-yl)methanone

Sources & evidence

ORD record
ord-adadc634c0a4490ca27aff0fdf160c90
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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