1-(3-Fluoro-4-piperazin-1-ylphenyl)ethanone → 3-[4-(4-Acetyl-2-fluoro-phenyl)-piperazine-1-carbonyl]-4-bromo benzonitrile
Reaction equation
[Br:17][c:18]1[c:19]([C:20](=[O:21])[OH:22])[cH:23][c:24]([C:27]#[N:28])[cH:25][cH:26]1.[F:1][c:2]1[cH:3][c:4]([C:14]([CH3:15])=[O:16])[cH:5][cH:6][c:7]1[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1>>[F:1][c:2]1[cH:3][c:4]([C:14]([CH3:15])=[O:16])[cH:5][cH:6][c:7]1[N:8]1[CH2:9][CH2:10][N:11]([C:20]([c:19]2[c:18]([Br:17])[cH:26][cH:25][c:24]([C:27]#[N:28])[cH:23]2)=[O:21])[CH2:12][CH2:13]1Participants
3
Sources & evidence
- ORD record
- ord-5ed33f67057147a8acf5e4791ffd2d3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…