HuagongsheHuagongshe Chemistry Print Report · For research reference only
Selenium Dioxide → 6-Methoxy-1,3-benzothiazole-2-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | 6-Methoxy-2-methylbenzothiazole | HCID 76254 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 6-Methoxy-1,3-benzothiazole-2-carbaldehyde | HCID 14598981 | 55.5% |
Reaction Steps
Oxidation of 6-methoxy-2-methylbenzothiazole (10.0 g, 55.9 mmole) with selenium dioxide (6.2 g, 55.9 mmole) in 300 ml dioxane for six hours by the method of Preparation H gave 6.0 g of 6-methoxy-2-formylbenzothiazole after chromatography of the crude product on silica gel, eluting with chloroform. 1H-NMR(CDCl3)-ppm(delta): 3.9 (s, 3H), 7.1-7.5 (m, 2H), 8.0-8.3(m, 1H), 10.1 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05015473 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-2c5bac721512431480f0c45ebb6700b8 |
| Source note | uspto-grants-1991_05 |