Ethyl Bromide → HCID 19833860, compound

Participants

Reaction Steps

In a flask maintained under nitrogen and equipped with a mechanical stirrer, a suspension of K2CO3 (29.5 g, 0.241 mole) in an acetone (200 ml) solution of 2,2-dimethyl-6-methylene-1-cyclohexanecarboxylic acid (30.0 g, 0.179 ml) and ethyl bromide (23.3 g, 0.214 mole) was warmed up to reflux. After 2 h 30, the temperature was allowed to cool to 25° and the reaction mixture was poured on 5% NaOH, extracted with ether (twice), washed with H2O and sat. NaCl, dried over Na2SO4, filtered and the solvents evaporated. Distillation of the crude product yielded, at 90°/5.3×102Pa, 32.3 g of the desired ester (yield: 92%).

Provenance & Evidence