ethyl N-(2-hydroxyethyl)carbamate → 2-ethoxycarbonylamino-ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 2050800Notes

Reaction equation

HRID 2050800 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16]#[N:17])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[OH:18][CH2:19][CH2:20][NH:21][C:22](=[O:26])[O:23][CH2:24][CH3:25]>>[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:17])[O:18][CH2:19][CH2:20][NH:21][C:22]([O:23][CH2:24][CH3:25])=[O:26])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 223805ethyl N-(2-hydroxyethyl)carbamateHCID 198338865,7-dihydro-6H-dibenz[c,e]azepine-6carbonitrile

Product 1

HCID 198338992-ethoxycarbonylamino-ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Procedure

starting from 5,7-dihydro-6H-dibenz[c,e]azepine-6-carbonitrile and ethyl 2-hydroxy-ethylcarbamate, there is obtained 2-ethoxycarbonylamino-ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate as a resinous product, mass spectrum m/e: M+ 353 (2), 308 (4), 237 (32), 194 (78), 116 (100), 88 (61);

Sources & evidence

ORD record
ord-4e7d827f641f4bff8e57e2b6040b917c
Source dataset
uspto-grants-1991_05
Patent number
US05015640

Reaction notes

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