2-(Trifluoromethyl)benzoyl chloride → HCID 19833928, compound

HRID 2050839Notes

Reaction equation

HRID 2050839 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:20])[O:17][CH2:18][CH3:19])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[F:21][C:22]([F:33])([F:32])[C:23]1[CH:31]=[CH:30][CH:29]=[CH:28][C:24]=1[C:25](Cl)=[O:26]>>[F:21][C:22]([F:32])([F:33])[C:23]1[CH:31]=[CH:30][CH:29]=[CH:28][C:24]=1[C:25]([N:20]=[C:16]([N:7]1[CH2:6][C:5]2[CH:4]=[CH:3][CH:2]=[CH:1][C:11]=2[C:10]2[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=2[CH2:8]1)[O:17][CH2:18][CH3:19])=[O:26]

Participants

3

Reactant 2

HCID 675612-(Trifluoromethyl)benzoyl chlorideHCID 19833914ethyl 5,7-dihydro-6H-dibenz[c,e]azepine-6carboximidate

Product 1

HCID 19833928HCID 19833928, compound

Procedure

starting from ethyl 5,7-dihydro-6H-dibenz[c,e]azepine6-carboximidate and 2-trifluoromethylbenzoyl chloride, there is obtained ethyl N-(o-trifluoromethylbenzoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate, m,p. 122°-125° C.;

Sources & evidence

ORD record
ord-ebb39e603b184a88b578a6415a5ac694
Source dataset
uspto-grants-1991_05
Patent number
US05015640

Reaction notes

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