4-Fluorobenzoyl chloride → methyl N-(p-fluorobenzoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

HRID 2050855Notes

Reaction equation

HRID 2050855 reaction equation
[CH:1]1[C:11]2[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8][N:7]([C:16](=[NH:19])[O:17][CH3:18])[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=1>>[F:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([N:19]=[C:16]([N:7]2[CH2:6][C:5]3[CH:4]=[CH:3][CH:2]=[CH:1][C:11]=3[C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[CH2:8]2)[O:17][CH3:18])=[O:26])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 19833984methyl 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Product 1

HCID 19833900methyl N-(p-fluorobenzoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate

Procedure

starting from methyl 5,7-dihydro-6H-dibenz[c,e]-azepine-6-carboximidate and p-fluorobenzoyl chloride, there is obtained methyl N-(p-fluorobenzoyl)-5,7-dihydro-6H-dibenz[c,e]azepine-6-carboximidate, m.p. 136°-137.5° C.;

Sources & evidence

ORD record
ord-f7797218504c49249a891b77cd6318f7
Source dataset
uspto-grants-1991_05
Patent number
US05015640

Reaction notes

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