反应详情

In a pressure reactor was placed 10.4 g (0.043 mole) of 1-cyano-1-(4-diethylaminophenyl)cyclopentane, 100 mL of methanolic ammonia, and 10 g of Ra-Ni catalyst. The reactor was charged with hydrogen and shaken at room temperature until the theoretical amount of hydrogen was taken up. The reaction mixture was filtered and the filtrate concentrated in vacuo to yield 9.9 g of the desired amine.

1. customIn a pressure reactor was placed
2. filtrationThe reaction mixture was filtered
3. concentrationthe filtrate concentrated in vacuo