Water → HCID 54068677, compound

Participants

Reaction Steps

A mixture of 6.87 g (35.4 mmol) of 4-hydroxyphenyl-3-methylbut-2-enylsulfide, 12.96 g (126 mmol) of acetic anhydride and 10 ml of pyridine was heated at reflux for 1.5 hours under a nitrogen atmosphere. The reaction mixture was cooled to room temperature, poured into water and extracted with 2×50 ml ether. The ether extracts were combined and washed successively with water and saturated NaCl solution and then dried (MgSO4). The solution was filtered and the solvent removed in-vacuo to give the title compound as a pale yellow oil. PMR (CDCl3): δ1.55 (3H, s), 1.71 (3H, s), 2.29 (3H, s), 3.51 (2H, d, J~7.6 Hz), 5.28 (1H, m), 7.00 (2H, d, J~8.8 Hz), 7.35 (2H, d, J~8.8 Hz).

Provenance & Evidence