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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2051118Generated: November 1, 2026

Hydrochloric Acid → 2-Methylpyrazolo[1,5-a]pyrimidine

https://huagongshe.com/reaction/2051118

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetramethoxypropaneHCID 66019—
Reactant1H-Pyrazol-3-amine, 5-methyl-HCID 93146—
Product2-Methylpyrazolo[1,5-a]pyrimidineHCID 12773559—

Reaction Steps

3-Amino-5-methylpyrazole is reacted with 1,1,3,3-tetramethoxypropane under an acidic condition of hydrochloric acid and treated in a similar way to Reference Example 22 to give the title compound as a crystal. mp. 54°-57° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05017212
Source datasetuspto-grants-1991_05
ORD IDord-ff69ca68fa9141ce992684b025a678e4
Source noteuspto-grants-1991_05