HCID 14204650, compound → HCID 54555936, compound

HRID 2051158Notes

Reaction equation

HRID 2051158 reaction equation
[CH3:1][C:2]([C:10]1[CH:18]=[C:17](C(C)(C)C2C=CC=CC=2)[CH:16]=[C:12]([C:13]([OH:15])=[O:14])[C:11]=1[OH:28])(C)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C1(C2C=C(C(C)(C)C3C=CC=CC=3)C=[C:37]([C:38]([OH:40])=[O:39])[C:36]=2O)CCCCC1.C1(C2C=C(C(C)(C)C3C=CC(C(C)(C)C4C=CC=CC=4)=CC=3)C=C(C(O)=[O:64])C=2O)C=CC=CC=1.C1(C2C=C(C(C)(C)C3C=CC=CC=3)C=C(C(O)=O)C=2O)C=CC=CC=1>>[OH:64][C:1]1[C:37]([C:38]([OH:40])=[O:39])=[CH:36][C:8]2[C:3]([C:2]=1[C:10]1[CH:18]=[CH:17][CH:16]=[C:12]([C:13]([OH:15])=[O:14])[C:11]=1[OH:28])=[CH:4][CH:5]=[CH:6][CH:7]=2

Participants

5

Reactant 4

HCID 14204650HCID 14204650, compoundHCID 18006896HCID 18006896, compoundHCID 186712893-Cyclohexyl-2-hydroxy-5-(2-phenylpropan-2-yl)benzoic acidHCID 19832849HCID 19832849, compound

Product 1

HCID 54555936HCID 54555936, compound

Procedure

Of the above compounds, 3,5-di(α,α-dimethylbenzyl)salicylic acid, 3-[4'(α,α-dimethylbenzyl)-phenyl-5-(α,α-dimethylbenzyl)salicylic acid, 3-cyclohexyl-5-(α,α-dimethylbenzyl)salicylic acid, 3-phenyl-5-[4'-(α,α-dimethylbenzyl)-α,α-dimethylbenzyl]salicylic acid, and 3-phenyl-5-(α,α-dimethylbenzyl)salicylic acid are said to be most preferred.

Sources & evidence

ORD record
ord-7f9dcf2460c041f6924cad7501d95c96
Source dataset
uspto-grants-1991_05
Patent number
US05017546

Reaction notes

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