HuagongsheHuagongshe Chemistry Print Report · For research reference only
17beta-(Hydroxymethyl)androst-4-ene-3-ol → 17beta-Hydroxymethyl-4-androsten-3-on
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 17beta-(Hydroxymethyl)androst-4-ene-3-ol | HCID 14801334 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 17beta-Hydroxymethyl-4-androsten-3-on | HCID 14377617 | 96.6% |
Reaction Steps
A solution of 17β-(hydroxymethyl) -androst-4-ene 3 ol (27 g, 0.089 mol) in 1200 ml trichloromethane was treated with activated manganese dioxide (66 g). After 3 hours the mixture was filtered. Concentration afforded 26 g (96%) of 3-oxo-17β-(hydroxymethyl)-4 androstene (m.p. 151° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05017568 |
| Source dataset | uspto-grants-1991_05 |
| ORD ID | ord-658304117daf44e3b80ae272c5c9ec75 |
| Source note | uspto-grants-1991_05 |