HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2051386Generated: October 27, 2026
Methyl iodide → 4-bromo-N-benzoyl-1-methylaminoanthraquinone
https://huagongshe.com/reaction/2051386
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Benzamide, N-(4-bromo-9,10-dihydro-9,10-dioxo-1-anthracenyl)- | HCID 66478 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 4-bromo-N-benzoyl-1-methylaminoanthraquinone | HCID 19799445 | 98.1% |
Reaction Steps
A mixture of 4-bromo-1-benzoylaminoanthraquinone (purity 98.5%, 41.2 g), monochlorobenzene (500 g), tetra-n-butyl ammonium bromide (0.3 g) and 96% potassium hydroxide (12.0 g) was stirred for one hour at 30° C., and methyl iodide (28.4 g) was added thereto at 30° C. over 2 hours. A mixture was stirred at 30° C. for 30 minutes and 40° C. for 3 hours, successively. Then, the same aftertreatment as in Example 3 was conducted to obtain 4-bromo-N-benzoyl-1-methylaminoanthraquinone (41.8 g, purity 94.5%, yield 94.0%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05017713 |
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| Source dataset | uspto-grants-1991_05 |
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| ORD ID | ord-d62b05b76a314df29a8b02d68b0fca29 |
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| Source note | uspto-grants-1991_05 |
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