反应详情

A solution prepared by dissolving 16.7 g of 8-allyloxy-5-methyl-1,2,3,4,4a,9a-hexahydro-9-fluorenone in 70 ml of tetralin was refluxed under heating for 10 hours. Tetralin was distilled off under reduced pressure and then the residue was purified by a silica gel column chromatography (eluent: ethyl acetate:n-hexane=1:10) to obtain 12.63 g of 7-allyl-8-hydroxy-5-methyl-1,2,3,4,4a,9a-hexahydro-9-fluorenone.

1. customA solution prepared
2. temperaturewas refluxed
3. temperatureunder heating for 10 hours
4. distillationTetralin was distilled off under reduced pressure
5. customthe residue was purified by a silica gel column chromatography (eluent: ethyl acetate:n-hexane=1:10)