8-Hydroxy-5-methyl-7-nitro-1,2,3,4,4a,9a-hexahydro-9-fluorenone → 7-Amino-8-hydroxy-5-methyl-1,2,3,4,4a,9a-hexahydro-9-fluorenone

Participants

Reaction Steps

To 200 ml of ethanol were added 5.0 g of 8-hydroxy-5-methyl-7-nitro-1,2,3,4,4a,9a-hexahydro-9-fluorenone and 1 g of 5% palladium carbon and catalytic reduction was carried out at room temperature and under normal pressure. The catalyst was removed by filtration and the filtrate was concentrated to obtain 3.5 g of 7-amino-8-hydroxy-5-methyl-1,2,3,4,4a,9a-hexahydro-9-fluorenone (yellow crystal).

Provenance & Evidence