2-Amino-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → 6-({3-(Aminocarbonyl)-5-[2-fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)-N-(trans-4-hydroxycyclohexyl)pyridine-2-carboxamide
Reaction equation
[Br:21][c:22]1[cH:23][cH:24][cH:25][c:26]([C:28](=[O:29])[NH:30][CH:31]2[CH2:32][CH2:33][CH:34]([OH:37])[CH2:35][CH2:36]2)[n:27]1.[NH2:1][c:2]1[s:3][c:4](-[c:10]2[c:11]([F:20])[cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9]>>[NH:1]([c:2]1[s:3][c:4](-[c:10]2[c:11]([F:20])[cH:12][c:13]([C:16]([CH3:17])([CH3:18])[OH:19])[cH:14][cH:15]2)[cH:5][c:6]1[C:7](=[O:8])[NH2:9])[c:22]1[cH:23][cH:24][cH:25][c:26]([C:28](=[O:29])[NH:30][CH:31]2[CH2:32][CH2:33][CH:34]([OH:37])[CH2:35][CH2:36]2)[n:27]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-ec44a5ba8d6d4193a591e8dc05fb23ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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