Maleate(2-) → HCID 86744808, compound

HRID 2051572Notes

Reaction equation

HRID 2051572 reaction equation
[CH3:1][C:2]1[N:6](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[CH:5]=[N:4][C:3]=1/[CH:26]=[CH:27]/[C:28]([C:30]1[CH:39]=[CH:38][C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH:31]=1)=[O:29].[C:40]([O-:47])(=[O:46])/[CH:41]=[CH:42]\[C:43]([O-:45])=[O:44]>>[C:40]([OH:47])(=[O:46])/[CH:41]=[CH:42]\[C:43]([OH:45])=[O:44].[CH3:1][C:2]1[NH:6][CH:5]=[N:4][C:3]=1[CH:26]=[CH:27][C:28]([C:30]1[CH:39]=[CH:38][C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH:31]=1)=[O:29]

Participants

3

Reactant 2

HCID 5288227Maleate(2-)HCID 14987240HCID 14987240, compound

Product 1

HCID 86744808HCID 86744808, compound

Procedure

The deprotection of (E)-3-(5-methyl-1-(triphenylmethy)-1H-imidazol-4-yl]-1-(2-naphthalenyl)-2-propen-1-one (1.25 g) followed by maleate formation gave the title compound (0.75 g), m.p. 190°-191° (decomp.).

Sources & evidence

ORD record
ord-92789e5436db47a7b1096fa4b04a9593
Source dataset
uspto-grants-1991_05
Patent number
US05019586

Reaction notes

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