Diketene → HCID 20379294, compound

HRID 2051616Notes

Reaction equation

HRID 2051616 reaction equation
[CH2:1]=[C:2]1[O:6][C:4](=[O:5])[CH2:3]1.[NH:7]=[C:8]1[N:12]([CH3:13])[CH2:11][CH2:10][S:9]1>C(O)C>[C:4]([N:7]=[C:8]1[N:12]([CH3:13])[CH2:11][CH2:10][S:9]1)(=[O:5])[CH2:3][C:2]([CH3:1])=[O:6]

Participants

4

Reactant 2

HCID 12661DiketeneHCID 773183-Methyl-1,3-thiazolidin-2-imine

Product 1

HCID 20379294HCID 20379294, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

A solution of 13 g. of diketene in 100 ml. of ethanol was added dropwise to an ice-cold solution of 18 g. of 2-imino-3-methylthiazolidine in 100 ml. of ethanol. The mixture was allowed to warm spontaneously to room temperature and then evaporated to dryness. The residue was triturated with ether, collected on a filter and dried in a dessicator to give 2-acetoacetylimino-3-methylthiazolidine, m.p. 43°-45° C.

Workup

  1. customevaporated to dryness
  2. customThe residue was triturated with ether
  3. customcollected on
  4. filtrationa filter
  5. customdried in a dessicator

Sources & evidence

ORD record
ord-6148cb7146634080b4e1a465048eeb32
Source dataset
uspto-grants-1980_01
Patent number
US04181661

Reaction notes

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