Butylamine → 2-Benzoyl-3-butylaminocrotononitrile

HRID 2051629Notes

Reaction equation

HRID 2051629 reaction equation
[C:1](/[C:9](=[C:12](/OC)\[CH3:13])/[C:10]#[N:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:16]([NH2:20])[CH2:17][CH2:18][CH3:19]>>[C:1](/[C:9](=[C:12](/[NH:20][CH2:16][CH2:17][CH2:18][CH3:19])\[CH3:13])/[C:10]#[N:11])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 8007ButylamineHCID 234685002-Benzoyl-3-methoxycrotononitrile

Product 1

HCID 705280432-Benzoyl-3-butylaminocrotononitrile

Procedure

A sample of 2.5 g. of 2-benzoyl-3-methoxycrotononitrile is dissolved in 10 ml. of n-butylamine. The solution is sealed in a stainless steel bomb and heated on a steam bath overnight. The bomb is then opened and the solvent evaporated under reduced pressure. A greenish oil is obtained which is distilled on a Kugelrohr apparatus at 200° C./0.1 mm. to obtain the yellow oily product.

Workup

  1. temperatureheated on a steam bath overnight
  2. customthe solvent evaporated under reduced pressure
  3. customA greenish oil is obtained which
  4. distillationis distilled on a Kugelrohr apparatus at 200° C./0.1 mm
  5. customto obtain the yellow oily product

Sources & evidence

ORD record
ord-ec7522ee6f3f4b73ace8ec19702a77dd
Source dataset
uspto-grants-1980_01
Patent number
US04181677

Reaction notes

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