1,3-Butadiene → HCID 537535, compound

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Reaction Steps

1,7-Octadien-3-ol, Compound (III), which is the starting material for preparing 1,7-octadien-3-one of this invention can easily be synthesized by dimerizing butadiene using a palladium complex as a catalyst in the presence of acetic acid to obtain 3-acetoxy-1,7-octadiene, Compound (I), and then hydrolyzing the same. (See Tetrahedron Letters, No. 26, page 2451, 1967 incorporated herein by reference which teaches the synthesis of 4-acetoxy-2,7-octadiene and 1-acetoxy-2,7-octadiene by dimerizing butadiene in the presence of a bis(triphenyl phosphine) (maleic anhydride) palladium catalyst and acetic acid at 120° C.)

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