HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromopyruvic Acid → 3-(Bromomethyl)-1,2-dihydroquinoxalin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromopyruvic Acid | HCID 70684 | — |
| Reactant | 1,2-Diaminobenzene (D4, 98%) | HCID 10772950 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(Bromomethyl)-1,2-dihydroquinoxalin-2-one | HCID 286254 | — |
Reaction Steps
O-phenylenediamine (1.0 g., 0.0092 mol.) was dissolved in tetrahydrofuran (50 ml.) and 3-bromopyruvic acid (1.7 g., 0.0102 mol.) added. The reaction mixture was stirred at room temperature for one hour, during which time the product precipitated as a yellow solid. The product was collected by filtration and crystallized from methylene chloride. (0.91 g., m.p. 221-223° (dec.) 41%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04181724 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-0cd897205f3b4ec4911b5badbac65820 |
| Source note | uspto-grants-1980_01 |