HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → [5-Methoxy-2-methyl-1-(4-nitrobenzoyl)-1H-indol-3-yl]acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | HCID 20379446 | HCID 20379446 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | [5-Methoxy-2-methyl-1-(4-nitrobenzoyl)-1H-indol-3-yl]acetic acid | HCID 12845005 | — |
Reaction Steps
A solution of 4.9 g (12.8 mmol) of methyl-1-(p-nitrobenzoyl)-5-methoxy-2-methyl-3-indolylacetate in 40 ml of acetic acid containing 400 mg of p-toluene-sulfonic acid is refluxed for 20 hours and then concentrated in vacuo. p The gummy residue is extracted with ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04181740 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-ec2613ae136d49028be3f35a3a910d7c |
| Source note | uspto-grants-1980_01 |