(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal → Diacetone-D-glucose

Participants

Reaction Steps

The process of claim 1 where the 1,2:5,6-di-O-isopropylidene-3-amino-3-deoxy-α-D-allofuranose is prepared by reacting D-glucose with acetone to produce 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose, oxidizing the glucofuranose to produce 1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose-3-ulose, subjecting the hexofuranose to oximization to produce 1,2:5,6-di-O-isopropylidene-α-D-ribo-hexofuranose-3-ulose oxime, and reducing the oxime to produce said 1,2:5,6-di-O-isopropylidene-3-amino-3-deoxy-α-D-allofuranose.

Provenance & Evidence