HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl oxalate → HCID 178499141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl oxalate | HCID 11120 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 56997143 | HCID 56997143 | — |
| Reactant | HCID 57071968 | HCID 57071968 | — |
| Product | HCID 178499141 | HCID 178499141 | — |
Reaction Steps
In the manner described in Example (1a) 36.9 g (0.01 mol) of 2-(benzhydrylformyl)-amino-3-oxo-succinic acid dimethyl ester (prepared by reacting (benzhydrylformyl)-aminoacetic acid methyl ester with oxalic acid dimethyl ester in the presence of sodium methylate) were reacted with 18 g of potassium thiocyanate for 48 hours at 50° C. The 1-benzhydryl-2-mercapto-4,5-dimethoxycarbonyl-imidazole formed crystallized on adding hexane. Yield 33.2 g (87% of the theory), m.p. 154° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182624 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-19fb1ce44dc5472282627480daadb6cc |
| Source note | uspto-grants-1980_01 |