Sodium Hydroxide → HCID 20378065, compound

HRID 2051745Notes

Reaction equation

HRID 2051745 reaction equation
[O:1]1[CH2:5][CH2:4][O:3][C:2]1([C:11]([O:13]CC)=[O:12])[C:6]([O:8]CC)=[O:7].[OH-].[Na+:17]>CO>[O:1]1[CH2:5][CH2:4][O:3][C:2]1([C:6]([O-:8])=[O:7])[C:11]([O-:13])=[O:12].[Na+:17].[Na+:17]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 12347879Diethyl 1,3-dioxolane-2,2-dicarboxylate

Product 1

HCID 20378065HCID 20378065, compoundYield 96.1%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

A solution of 11.0 g (0.05 mol) of diethyl 1,3-dioxolane-2,2-dicarboxylate of Example 1 in 50 ml methanol was slowly added to a solution of 8.8 g of 50% aqueous sodium hydroxide (0.11 mol) in 100 ml. methanol. After stirring overnight the mixture was filtered and the salt washed twice with methanol, twice with ether and vacuum dried at 80° yielding 9.9 g (95%) of the title compound as a white solid.

Workup

  1. filtrationwas filtered
  2. washthe salt washed twice with methanol, twice with ether and vacuum
  3. customdried at 80°

Sources & evidence

ORD record
ord-ff5c232e434a4cbab75e8aa1f3091326
Source dataset
uspto-grants-1980_01
Patent number
US04182718

Reaction notes

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