HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(methylthio)-1H-naphtho[2,3-d]imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1H-benzo[f]benzimidazole-2-thiol | HCID 178527755 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-(methylthio)-1H-naphtho[2,3-d]imidazole | HCID 12872079 | 122.3% |
Reaction Steps
20.0 g of 1H-naphth[2,3-d]imidazole-2-thiol and 4.0 g of sodium hydroxide were heated for 1 hour under reflux and in 150 ml of ethanol with 6.5 g of methyl iodide. The reaction solution was diluted with 500 ml of water and the precipitated product was suction filtered. Crystallisation from dioxane provided 12.0 g of 2-methylthio-1H-naphth[2,3-d]imidazole haing a m.p. of 242°-244°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182766 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-c29e487f7c8c47c19a6b60ed76268379 |
| Source note | uspto-grants-1980_01 |