HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 2-Pyridinemethanol, 5-methyl-, 2-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 2,5-Dimethylpyridin-1-ium-1-olate | HCID 571773 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-Pyridinemethanol, 5-methyl-, 2-acetate | HCID 12325384 | — |
Reaction Steps
11.5 g of 2,5-dimethylpyridine-N-oxide in 5 ml of acetic acid were added dropwise to 18 ml of acetic anhydride pre-heated to 120°. The reaction solution was boiled under reflux for a further 45 minutes, concentrated by evaporation on a rotary evaporator, and distilled at 8 mm Hg/115°. 14.0 g of 2-acetoxymethyl-5-methylpyridine was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182766 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-3f47da391fdb4b7e81858e0412059940 |
| Source note | uspto-grants-1980_01 |