反应详情

A mixture of 100 g (0.43 mole) of 2-amino-5-chlorobenzophenone and 500 g formic acid was refluxed for 1 hr, and then cooled and poured into 1 l. of ice water. The solid that precipitated was collected on a filter, washed with water, dried in air, and recrystallized from heptane-benzene to give 103.5 g (93%) of the formamide as colorless crystals, mp 89°-91°.

1. temperaturewas refluxed for 1 hr
2. temperaturecooled
3. additionpoured into 1 l
4. customThe solid that precipitated
5. customwas collected on a filter
6. washwashed with water
7. customdried in air
8. customrecrystallized from heptane-benzene