Butylamine → HCID 53956630, compound

HRID 2051833Notes

Reaction equation

HRID 2051833 reaction equation
O=[CH:2][C@@H:3]([C@@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH2:11]([NH2:15])[CH2:12][CH2:13][CH3:14].[Cl:16][CH2:17][CH2:18][N:19]=[C:20]=[O:21]>>[Cl:16][CH2:17][CH2:18][NH:19][C:20]([N:15]([CH2:11][CH2:12][CH2:13][CH3:14])[CH:2]1[O:8][C@H:7]([CH2:9][OH:10])[C@@H:5]([OH:6])[C@H:3]1[OH:4])=[O:21]

Participants

4

Reactant 3

HCID 8007ButylamineHCID 160352-Chloroethyl isocyanateHCID 5311110Aldehydo-D-ribose

Product 1

HCID 53956630HCID 53956630, compoundYield 80.5%

Procedure

3.0 g of D-ribose, 1.9 g of n-butylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 5-(1). 5.0 g of 1-(2-chloroethyl)-3-n-butyl-3-D-ribofuranosylurea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-1ec5d23d57cb49d9a349df07e64cf33b
Source dataset
uspto-grants-1980_01
Patent number
US04182757

Reaction notes

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