HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Ethyl (2-acetamido-3-benzoylphenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Ozone | HCID 24823 | — |
| Reactant | Ethyl (2-methyl-3-phenyl-1H-indol-7-yl)acetate | HCID 23342680 | — |
| Product | Ethyl (2-acetamido-3-benzoylphenyl)acetate | HCID 54304647 | — |
Reaction Steps
A solution of 5 g. (0.017 mole) of ethyl α-(2-methyl-3-phenylindol-7-yl)acetate and 75 ml. of acetic acid was treated with ozone for 25 minutes. After ozonation, the acetic acid solution was diluted with water and extracted with ether. The ether extracts were washed with water, 5% sodium carbonate, dried (magnesium sulfate) and concentrated. Recrystallization from isopropanol gave 2.6 g. (47%) of product which melted at 133°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182774 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-e41521fd0c30499ca37edd637820198d |
| Source note | uspto-grants-1980_01 |