反应详情

A mixture of 16.5 g of ethyl p-aminobenzoate, 10.3 g of 11-phenoxy-1-undecanol O-methanesulfonate and 50 ml of hexamethylphosphoramide is heated at 100°-110° C. for 20 hours, chilled, and diluted with 30 ml of ethanol and 10 ml of water. Chilling and filtering gives a solid which is washed with ethanol-water (1:1) and with water to give yellow crystals, mp 83°-87° C. Recrystallization from ethanol gives yellow needles, mp 89°-90° C.

1. temperatureis heated at 100°-110° C. for 20 hours
2. temperaturechilled
3. temperatureChilling
4. filtrationfiltering
5. customgives a solid which
6. washis washed with ethanol-water (1:1) and with water
7. customto give yellow crystals, mp 83°-87° C
8. customRecrystallization from ethanol
9. customgives yellow needles, mp 89°-90° C.