HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzocaine → HCID 20378391, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzocaine | HCID 2337 | — |
| Reactant | Hexamethylphosphoramide | HCID 12679 | — |
| Reactant | Benzene, (3-bromopropoxy)- | HCID 68522 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 20378391 | HCID 20378391 | — |
Reaction Steps
A mixture of 33 g of ethyl p-aminobenzoate, 21.5 g of 3-bromopropylphenyl ether and 100 ml of hexamethylphosphoramide is heated at 100°-110° C. in an oil bath for 20 hours. The mixture is chilled, diluted with 50 ml of water, chilled and filtered. The solid is washed with ethanol-water (1:1) and with water to give yellow crystals, mp 73°-74° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182776 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-c0e64f51e3734172a142fa3a0602ce30 |
| Source note | uspto-grants-1980_01 |