5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine → 1-((2-(6-aminopyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-N-methylpiperidine-4-carboxamide

HRID 205199Notes

Reaction equation

HRID 205199 reaction equation
[CH3:1][NH:2][C:3](=[O:4])[CH:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[n:15][c:16]([Cl:27])[n:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[c:19]3[s:20]2)[CH2:9][CH2:10]1.[CH3:28][C:29]1([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34][B:35]([c:36]2[cH:37][cH:38][c:39]([NH2:42])[n:40][cH:41]2)[O:43]1>>[CH3:1][NH:2][C:3](=[O:4])[CH:5]1[CH2:6][CH2:7][N:8]([CH2:11][c:12]2[cH:13][c:14]3[n:15][c:16](-[c:36]4[cH:37][cH:38][c:39]([NH2:42])[n:40][cH:41]4)[n:17][c:18]([N:21]4[CH2:22][CH2:23][O:24][CH2:25][CH2:26]4)[c:19]3[s:20]2)[CH2:9][CH2:10]1

Participants

3

Reactant 2

HCID 27565555-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amineHCID 574939941-(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-piperidine-4-carboxylic acid methylamide

Product 1

HCID 249472351-((2-(6-aminopyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)-N-methylpiperidine-4-carboxamide

Sources & evidence

ORD record
ord-0379e3a1ef88445fa3e003c41ef51729
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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