HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formic Acid → N-(4-Methylbenzoyl)phosphoramidic dichloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formic Acid | HCID 284 | — |
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | 4-Methylbenzamide | HCID 69274 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | N-(4-Methylbenzoyl)phosphoramidic dichloride | HCID 14115791 | — |
Reaction Steps
A mixture of 53 g (0.39 mole) of 4-methylbenzamide, 81.7 g (0.39 mole) of phosphorus pentachloride and 500 ml of AR carbon tetrachloride was heated at 60°-70° until the HCl gas evolution had ceased. Solution was cooled to 30° where 18.6 g (0.39 mole) of 97% formic acid was added. Continued to stir for 30 min. following the addition, then filtered, washed with AR carbon tetrachloride and air-dried to give 74.5 g, m.p. 96.5°-98°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04182881 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-5e357bac1a8a4e8bb0dce389bd4731f2 |
| Source note | uspto-grants-1980_01 |