2-Bromobenzyl alcohol → 2-Bromobenzyl 2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

HRID 205213Notes

Reaction equation

HRID 205213 reaction equation
[Br:28][c:29]1[c:30]([CH2:35][OH:36])[cH:31][cH:32][cH:33][cH:34]1.[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([c:16]2[s:17][cH:18][c:19]([C:21](=[O:22])[OH:23])[n:20]2)[CH2:14][CH2:15]1>>[CH3:1][c:2]1[cH:3][c:4]([C:24]([F:25])([F:26])[F:27])[n:5][n:6]1[CH2:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][CH:13]([c:16]2[s:17][cH:18][c:19]([C:21](=[O:22])[O:23][CH2:35][c:30]3[c:29]([Br:28])[cH:34][cH:33][cH:32][cH:31]3)[n:20]2)[CH2:14][CH2:15]1

Participants

3

Reactant 2

HCID 728502-Bromobenzyl alcoholHCID 666014572-[1-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-4-piperidinyl]-4-thiazolecarboxylic acid

Product 1

HCID 669115082-Bromobenzyl 2-(1-{[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

Sources & evidence

ORD record
ord-5cf04b07da744227aa995b56ac648f54
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…