Formic Acid → HCID 20378760, compound

HRID 2052135Notes

Reaction equation

HRID 2052135 reaction equation
[CH3:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[P:12]([Cl:17])(Cl)(Cl)(Cl)[Cl:13].C(O)=[O:19]>C(Cl)(Cl)(Cl)Cl>[Cl:13][P:12]([Cl:17])([NH:6][C:4](=[O:5])[C:3]1[CH:7]=[CH:8][CH:9]=[C:10]([CH3:11])[C:2]=1[CH3:1])=[O:19]

Participants

5

Reactant 3

HCID 284Formic AcidHCID 24819Phosphorus pentachlorideHCID 28009872,3-dimethylbenzamide

Product 1

HCID 20378760HCID 20378760, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

Heated at 70° for 30 min. a mixture containing 23.3 g (0.16 mole) of 2,3-dimethylbenzamide, 32.5 g (0.16 mole) of phosphorus pentachloride and 250 ml of AR carbon tetrachloride. The resulting solution was cooled to 30° and 7.4 g (0.16 mole) of 97% formic acid added. Continued to stir at 30° for 20 min. then chilled to 0°, filtered, washed with AR carbon tetrachloride and air-dried to give 36.1 g, m.p. 88°-90°.

Workup

  1. temperatureHeated at 70° for 30 min. a mixture
  2. temperatureThe resulting solution was cooled to 30°
  3. temperaturethen chilled to 0°
  4. filtrationfiltered
  5. washwashed with AR carbon tetrachloride
  6. customair-dried
  7. customto give 36.1 g, m.p. 88°-90°

Sources & evidence

ORD record
ord-f59b241a8e55405f8866bf8e0ddc0021
Source dataset
uspto-grants-1980_01
Patent number
US04182881

Reaction notes

Loading…