Formic Acid → Phosphoramidic dichloride, (4-butoxybenzoyl)-

Participants

Reaction Steps

A mixture of 76 g (0.39 mole) of 4-butoxybenzamide, 81.9 g (0.39 mole) of phosphorus pentachloride and 700 ml of AR carbon tetrachloride was heated at 70° for 30 min. The resulting solution was cooled to 30° and 18.7 g (0.39 mole) of 97% formic acid was added. The reaction was chilled to 0°, filtered, washed with AR carbon tetrachloride and air-dried to give 52.1 g, m.p. 97°-98°.

Provenance & Evidence