Trifluoroacetic acid → HCID 131711677, compound

Participants

Reaction Steps

A mixture of 0.07 g of benzhydryl 7-(2-methoxyimino-2-phenylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)-3-cephem-4-carboxylate (obtained in Example 59), 2 ml of anisole and 4 ml of trifluoroacetic acid is stirred for 30 minutes at room temperature. After removal of the solvent under reduced pressure, the residue is triturated with the addition of absolute ether. The precipitates are filtered, and washed with ether to give 0.046 g of 7-(2-methoxyimino-2-phenylacetamido)-3-(5-methyl-1,3,4-thiadiazol-2-yl)-3-cephem-4-carboxylic acid.

Provenance & Evidence