反应详情

温度

100 °C

2-(4-Pyridyl)-s-triazolo[1,5-a]pyridine (10.0g), prepared as in Example I stage (a) was added to ethyl bromoacetate (25 ml). The mixture was heated to 100° C. for 1 hour, cooled and diluted with ether (80 ml). The solid which formed was filtered off, washed with ether and dried. Recrystallisation from methanol yielded 13.9g of 2-(1-ethoxycarbonylmethylpyridinium-4-yl)-s-triazolo[1,5-a]pyridine bromide, m.p. 174°-176° C.

1. temperaturecooled
2. customThe solid which formed
3. filtrationwas filtered off
4. washwashed with ether
5. customdried
6. customRecrystallisation from methanol