HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isoxazolamine, 5-(1,1-dimethylethyl)- → N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N-ethyl-N-methylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isoxazolamine, 5-(1,1-dimethylethyl)- | HCID 171473 | — |
| Reactant | N-Ethyl-N-methylcarbamoyl chloride | HCID 11240471 | — |
| Product | N'-(5-tert-Butyl-1,2-oxazol-3-yl)-N-ethyl-N-methylurea | HCID 20377186 | 96.1% |
Reaction Steps
Using 3-amino-5-t-butylisoxazole and N-ethyl-N-methylcarbamoyl chloride, the reaction is carried out as in Example 1, whereby 1-ethyl-1-methyl-3-(5-t-butyl-3-isoxazolyl)urea is obtained. Yield is 96.1%. Melting point is 88.5° to 89.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04183856 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-59e1e22ca06e4113b88daf0baf0e3cfc |
| Source note | uspto-grants-1980_01 |