Benzylamine → 3-Benzyl-3-azabicyclo(3.1.0)hexane-2,4-dione

HRID 2052221Notes

Reaction equation

HRID 2052221 reaction equation
[CH:1]1([C:7]([OH:9])=O)[CH2:3][CH:2]1[C:4](O)=[O:5].[CH2:10]([NH2:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([N:17]1[C:7](=[O:9])[CH:1]2[CH:2]([CH2:3]2)[C:4]1=[O:5])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 136524Cyclopropane-1,2-dicarboxylic acid

Product 1

HCID 27645863-Benzyl-3-azabicyclo(3.1.0)hexane-2,4-dione

Procedure

1,2-cyclopropanedicarboxylic acid is treated with benzylamine to form 3-(benzyl)-3-azabicyclo(3.1.0)hexane-2,4-dione (I).

Sources & evidence

ORD record
ord-88ea4f0b5c8145d8b5bbe70aaba3e8b9
Source dataset
uspto-grants-1980_01
Patent number
US04183857

Reaction notes

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