Water → HCID 135737543, compound

Participants

Reaction Steps

To a suspension of 1.38 g of 7-methoxy-5-phenylimidazo[1,2-a]quinazoline in 25 ml of tetrahydrofuran was added 0.38 g of lithium aluminum hydride, and the mixture was stirred at room temperature for 3 hours. To the reaction mixture was added dropwise 1 ml of water with ice-cooling, and the resulting precipitate was filtered off and washed with tetrahydrofuran. The filtrate was evaporated under reduced pressure and the residue was recrystallized from ethylacetate-isopropyl ether to give 1.1 g of 4,5-dihydro-7-methoxy-5-phenylimidazo[1,2-a]quinazoline, m.p. 178°-179° C. (decomp.).

Provenance & Evidence