HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Heptanone, 1-(triphenylphosphoranylidene)- → 6-(7-Hydroxyheptyl)-7-(5-ethoxy-3-oxopent-1-enyl)-1,4-dioxaspiro[4,4]nonane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Heptanone, 1-(triphenylphosphoranylidene)- | HCID 10761944 | — |
| Reactant | 1-Chloroheptan-2-one | HCID 10953678 | — |
| Reactant | 1-Chloro-4-ethoxybutan-2-one | HCID 14068889 | — |
| Reactant | 3-Ethoxypropionylmethylenetriphenylphosphorane | HCID 20542922 | — |
| Reactant | 4-Ethoxy-2-oxobutyltriphenylphosphonium chloride | HCID 85855197 | — |
| Product | 6-(7-Hydroxyheptyl)-7-(5-ethoxy-3-oxopent-1-enyl)-1,4-dioxaspiro[4,4]nonane | HCID 57012013 | — |
Reaction Steps
The 3-ethoxypropionylmethylenetriphenylphosphorane (m.p. 63°-65° C.), used as a starting material in the above preparation, was prepared from 1-chloro-4-ethoxybutan-2-one, via 4-ethoxy-2-oxobutyltriphenylphosphonium chloride (m.p. 157°-160° C.), by proceeding in a similar manner to that hereinbefore described in Example 3(i) for the preparation of hexanoylmethylenetriphenylphosphorane from 1-chloroheptan-2-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04183870 |
| Source dataset | uspto-grants-1980_01 |
| ORD ID | ord-5f537544f5df48e3b4e9ef9699ca30f4 |
| Source note | uspto-grants-1980_01 |